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Vectra DA (New test)
|Approval req'd?||Yes, for any inpatient orders|
|Utilization Guidelines||This test should ONLY be ordered for monitoring patients with Rheumatoid arthritis (RA). It is not intended for diagnosis of RA nor should it be used to monitor patients with other non-RA autoiimmune disorders.
Note that this test should NOT be ordered in conjunction with C-reactive Protein (CRP) as that inflammatory marker is part of the Vectra panel.
|Performed by||Crescendo Bioscience|
|Collection Instructions||Collect Monday-Friday before noon for same day shipping. Samples cannot be collected after noon on Fridays.
Please print and complete the Vectra Form and send with the sample to the laboratory:
Click here for form
|Container type||Gold top|
|Amount to Collect||4 mL blood|
|Preferred volume||4 mL serum|
|Min. Volume||4 mL serum|
|Processing notes||Allow to clot at room temperature (20-25°C) for 30-120 minutes. Centrifuge for 15 minutes (1100-1300 RCF at room temp). Do not aliquot. Transport tube and kit to CB. If sample cannot be shipped same day, store refrigerated until next day.|
|Normal range||See report|
|Synonyms||Rheumatoid arthritis; VectraDA; Vectra DA; MBDA; Multi-Biomarker Disease Activity test; RA Biomarker test; Crescendo Biomarker Test|
|Additional information||Note that this test should NOT be ordered in conjunction with C-reactive Protein (CRP) as that inflammatory marker is part of the Vectra panel.
Vectra DA provides an objective and reproducible measure of RA disease activity in both seropositive and seronegative RA patients.
The concentrations of 12 serum proteins are measured. An algorithm is then applied to calculate a single Vectra DA score ranging from 1 to 100 that categorizes RA into low, moderate, or high disease activity.
Vectra DA can provide a baseline assessment of RA disease activity and track it over time. Vectra DA is validated for use in adults diagnosed with RA.
Note: Acute non-RA associated inflammation, recent vaccination, trauma, surgery, infection (e.g. any inflammatory or immunologic stimulus) may all result in an elevated Vectra score that may not reflect the patients RA status. Therefore testing should be avoided when any of these conditions exist and for 10-14 days after they have subsided.
|Medical Necessity?||The test has a Medicare frequency limitation of 2x per year. An ABN will be automatically generated for this test regardless of the ICD-9 codes provided. Applicable ICD-9 codes are: 714.00, 714.10,714.20,714.81|
|Last Updated||10/31/2013 3:40:42 PM|