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Cancer Antigen 15-3

Item Value
Approval req'd? No
Available Stat? No
Test code CA15
Performed by China Basin Chemistry
In House Availability Monday (day shift)
Method Chemiluminescent Immunoassay (Siemens Centaur)
Container type Gold top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.5 mL serum
UCSF Rejection Criteria Gross hemolysis
Processing notes Freeze serum at -20°C.
Units U/mL
Normal range < 33 U/mL
Synonyms CA15-3; CA15; CA27; CA 27.29
Turn around times 1-8 days
Additional information CA 15-3 is a serum marker commonly elevated in patients with breast cancer. It is a useful prognostic marker with higher levels being associated with advanced disease stage, and it can be used to monitor patients during and following treatment. CA 15-3 is neither a sensitive nor specific marker for early disease and should not be used for screening purposes. A small proportion of apparently healthy individuals (up to 5% of the general population) have an elevated CA 15-3 level as well as some patients with liver disease and other types of carcinoma. Clin Chem 52:345-351 2006.

Not covered by Medicare for screening purposes (Medicare Bulletin 98-7, December, 1998)
CPT coding 86300
Medical Necessity? Yes. Click here for more information
LOINC code 6875-9
Last Updated 3/25/2013 12:53:54 PM
Entry Number 153
Lab Procedure Link Click here for Procedure
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