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Nicotine and Cotinine, urine

Item Value
Available Stat? No
Test code NICUR
Performed by Quest
Sendout? Yes
Method LC/MS/MS
Container type Urine cup
Amount to Collect 10 mL urine
Sample type Random urine
Preferred volume 1 mL urine
Min. Volume 0.5 mL urine
Processing notes Aliquot and refrigerate sample. Transport to CB refrigerated. Order Quest test code 90646
Units ng/mL
Normal range Nicotine:
Smokers 200-700 ng/mL
Non-Smokers ≤ 17 ng/mL

Smokers 300-1300 ng/mL
Non-Smokers ≤ 20 ng/mL
Synonyms cigarette; smoking; tobacco
Stability Room temperature 3 days, refrigerated 2 weeks, frozen 1 month
Additional information This assay is used for the detection of nicotine and cotinine in serum and plasma to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; Its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.
CPT coding 83887-90
Last Updated 8/7/2014 9:50:38 AM
Entry Number 1528
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