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Histoplasma capsulatum Antigen

Item Value
Clinical Questions Does my patient have histoplasmosis?
Approval req'd? Yes, for testing requested on specimens other than urine.
Available Stat? No
Test code HISTAG
Test group Histoplasma
Performed by Quest
Sendout? Yes
Method Enzyme immunoassay
Container type
Urine Urine cup
Blood Gold top, Lavender top, Lt Green top, Red top
CSF CSF tube or sterile collection tube
BAL Black top tube
Amount to Collect
Urine 10 mL
Blood 4 mL
All other samples 2 mL
Sample type Random urine, EDTA or heparinized plasma, serum, CSF, BAL
Preferred volume
Urine 2 mL
Plasma or serum 2 mL
All other samples 2 mL
Min. Volume
Urine 0.5 mL
Plasma or serum 1 mL
All other samples 1 mL
UCSF Rejection Criteria Specimen submitted < 2 weeks after prior specimen.
Processing notes Order Quest test code #34441X
Units ng/mL
Normal range
<0.7 Negative
0.7-2.9 Borderline
>2.9 Moderate to strong positive
Synonyms H. capsulatum
Stability Room temperature 3 days, refrigerated 2 weeks, frozen at -20C 2 months
Turn around times Test performed Monday-Friday. Turnaround: 2-5 days.
Additional information Urine is the most sensitive specimen for diagnosis.

Sensitivity:
Disseminated infection: 92%
Severe pulmonary infection 80%
Self-limited pulmonary infection 34%
Chronic pulmonary infection 14%
CPT coding 87385-90
LOINC code 13971-7
Last Updated 11/21/2013 1:35:04 PM
Entry Number 1509
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