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Juvenile Myelomonocytic Leukemia Associated Exon Panel – Family F/U
|Utilization Guidelines||Tests with long turn-around times (i.e., Molecular based tests and Microarrays) should only be requested on an inpatient if the result is going to affect the inpatient management. If the patient will likely be discharged before the result will be available, the test should be requested after discharge. (NOTE: UCSF Medical Center is not reimbursed for inpatient testing).
An exception to the above may be appropriate if there is a possibility the patient will not survive to be discharged and the information is important for diagnosis and/or family decisions/management (e.g., recurrence risk).
|Performed by||Molecular Diagnositcs|
|In House Availability||Run 1st and 3rd Monday of every month, day shift only|
|Method||PCR and Sequencing (Roche 454 Jr)|
|Collection Instructions||Avoid hemolysis.
Due to stability issues these samples should only be collected Monday through noon Friday
|Amount to Collect||
|Sample type||EDTA whole blood, cultured fibroblasts or buccal swab|
|Processing notes||Do not freeze blood or bone marrow samples. Ship to CB as soon as possible.|
|Synonyms||JMML Panel; CBL exons 8 & 9; KRAS exons 2 & 3; NRAS exons 2 & 3; PTPN11 exons 3, 4 & 13|
|Turn around times||2-4 weeks|
|Additional information||An interpretation of this test by a laboratory physician will automatically be performed and billed for separately.
This sequencing panel sequences the following gen es: CBL exons 8 & 9; KRAS exons 2 & 3; NRAS exons 2 & 3; PTPN11 exons 3, 4 & 13
Targeted, single exon, germline and family follow-up studies will only be performed when the diagnostic mutation was determined by the UCSF Molecular Diagnostics lab, or a report from another CLIA lab can be provided. Otherwise, please order "JMML Associated Exon Panel (JMML)" for testing.
For questions, contact the Molecular Diagnostics laboratory at 415-514-8488
|CPT coding|| 81479, except for specific mutations
|LDT or Mod FDA?||Yes|
|Last Updated||9/10/2013 8:56:12 AM|
If you have additional questions regarding this test, please call: 415-353-1667