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C1 Esterase Inhibitor Deficiency Panel
|Patient Preparation||An 8 hour fast before specimen collection is preferred|
|Collection Instructions||Collect and allow to clot in ice slurry. Bring immediately to lab on ice.
Note special sample requirements for B&T patients
|Container type||Red top on ice (Gold top NOT acceptable)
Lavender top on ice for B&T patients
|Amount to Collect||6 mL blood|
EDTA Plasma for B&T patients
|Preferred volume||3 mL serum in 3 aliquots of 1 mL each|
|Min. Volume||0.5 mL serum each|
|UCSF Rejection Criteria||Not delivered on ice. Sample collected in Gold top|
|Processing notes||Centrifuge immediately under refrigeration. Freeze three separate aliquots at ≤ 60C in plastic tubes and ship on dry ice. Order Quest # 44768P, 298 and 44784P
Note that LabCorp requires EDTA plasma for B&T patients.
|Units||see normal ranges|
|Normal range|| C1EI activity (by decay of C1r):
|Synonyms||Angioedema Panel; C1-esterase inhibitor; angioneurotic edema; anti-C1r; C1r; C4DX/C4 ratio; HAE; HAN E; Hereditary angioneurotic edema|
|Turn around times||Test performed Tuesday and Thursday. Turnaround time: 3-8 days.|
|Additional information|| Includes C1EI activity, C1EI quantitation and C1q quantitation.
The results expected of these assays in the different clinical settings in which low C4 levels are seen are:
|Last Updated||6/21/2016 08:08:12|