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|Test Update Information||Effective March 15, 2011, C-peptide testing is being performed in-house using the same instrument-methodology (Siemens Centaur) that was used by Quest Diagnostics.|
|Performed by||China Basin Chemistry|
|Method||Chemiluminescent Immunoassay (Siemens Centaur)|
|Patient Preparation||Overnight fast is required before specimen collection.|
|Collection Instructions||Deliver to lab immediately. Call physician if patient is not fasting to see if the specimen is acceptable.|
|Container type||Gold top or Red top|
|Amount to Collect||2 mL blood|
|Preferred volume||1 mL serum|
|Min. Volume||0.4 mL serum|
|Processing notes||Separate serum from cells within 30 minutes of collection and freeze specimen at -20C.|
Reference range was adopted from Quest Diagnostics-San Juan Capistrano based on in-house validation studies performed using the same instrument-methodology (Siemens Centaur) on samples from adult subjects with normal FBS (70-99 mg/dL) and A1c (4.3-5.6%).
Note: if patient was not fasting the normal ranges may not apply.
Pediatric reference ranges not available for this immunoassay platform.
|Stability||Room temperature 1 day, refrigerated 1 week frozen at -20C 4 weeks, at -70C 1 year.|
|Turn around times||Test performed Thursdays.|
|Additional information||Obesity, high carbohydrate diet and inactivity increase levels of this hormone. The assay is cross-reactive with proinsulin, but not with insulin.
C-Peptide is useful in distinguishing insulin-secreting tumors, i.e., insulinomas, from exogenous insulin administration. C-Peptide concentrations are severely depressed or absent in Type I diabetes mellitus. It is also useful in monitoring patients who have received islet cell or pancreatic transplants.
|Last Updated||9/19/2012 8:48:35 AM|
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