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Item Value
Available Stat? No
Test code MOLT
Test group Oncology FISH
Performed by Mayo
Sendout? Yes
In House Availability Run 2x per week, Monday & Wednesday, day shift only
Method Fluorescent in-situ hybridization (FISH)
Collection Instructions For UCSF Samples (from remote sites) Click here for sample collection instructions

For NON-UCSF Samples Click here for Requisition form & Account set-up instructions. Note we only do institutional billing.
Container type
Sample type Formalin-fixed, paraffin-embedded tissue on three (3) unstained slides (5 microns thick) on charged glass. One adjacent hematoxylin and eosin stained (H&E) slide should also be included. Slides should be labeled with pathology case number and block identification.
Preferred volume 3 unstained slides (5 micron thick sections)
Min. Volume 1 unstained slides (5 micron thick sections)
Units Ratio of MYCN to CEP2 signals
Normal range 1.09 +/- 0.22
Synonyms N-MYC; NMYC
Stability Slides are stable indefinitely at room temperature
Turn around times 10-14 days
Additional information An interpretation of this test by a laboratory physician will automatically be performed and billed for separately.

MYCN (n-myc) amplification by FISH is designed to detect gain of the MYCN locus in tumors. Amplification of MYCN has been associated with poor prognosis in Neuroblastoma and Medulloblastoma.

The clinical interpretation of this test should be evaluated within the context of the patient's medical history, other diagnostic tests, and the histologic and immunohistochemical features of the tumor.

The test was validated by UCSF Clinical Laboratories to confirm performance characteristics, in compliance with current guidelines for clinical implementation.
CPT coding 88377-90
LDT or Mod FDA? Yes
Last Updated 12/22/2015 3:22:14 PM
Entry Number 1437
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