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If you have additional questions regarding this test, please call: 415-353-1667
|Test group||Oncology FISH|
|In House Availability||Run 2x per week, Monday & Wednesday, day shift only|
|Method||Fluorescent in-situ hybridization (FISH)|
|Collection Instructions||For UCSF Samples (from remote sites) Click here for sample collection instructions
For NON-UCSF Samples Click here for Requisition form & Account set-up instructions. Note we only do institutional billing.
|Sample type||Formalin-fixed, paraffin-embedded tissue on three (3) unstained slides (5 microns thick) on charged glass. One adjacent hematoxylin and eosin stained (H&E) slide should also be included. Slides should be labeled with pathology case number and block identification.|
|Preferred volume||3 unstained slides (5 micron thick sections)|
|Min. Volume||1 unstained slides (5 micron thick sections)|
|UCSF Rejection Criteria||All required slides not included. Insufficient tumor present on slide as determined by pathologist. Slides not labeled or not accompanied by completed requisition form.|
|Units||Ratio of MYC to CEP8 signals|
|Normal range||1.03 +/- 0.19|
|Stability||Slides are stable indefinitely at room temperature|
|Turn around times||10-14 days|
|Additional information||An interpretation of this test by a laboratory physician will automatically be performed and billed for separately.
MYC (c-myc) amplification by FISH is designed to detect gain of the MYC locus in tumors. Amplification of MYC has been associated with poor prognosis in Medulloblastoma.
The clinical interpretation of this test should be evaluated within the context of the patient's medical history, other diagnostic tests, and the histologic and immunohistochemical features of the tumor.
The test was validated by UCSF Clinical Laboratories to confirm performance characteristics, in compliance with current guidelines for clinical implementation.
|LDT or Mod FDA?||Yes|
|Last Updated||6/22/2015 10:21:25 AM|