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Paraneoplastic Antibody Evaluation, CSF

Item Value
Approval req'd? No
Available Stat? No
Test code PAECSF
Test group Paraneoplastic antibodies
Performed by Mayo
Sendout? Yes
Method IFA
Container type CSF tube or sterile collection tube
Amount to Collect 4 mL CSF
Sample type CSF
Preferred volume 4 mL CSF
Min. Volume 3 mL CSF
Processing notes Freeze CSF and ship frozen to China Basin
Units Titer
Normal range
Antibody Titer
Antineuronal Nuclear Antibody-Type 1 (ANNA-1) Negative at <1:2
Antineuronal Nuclear Antibody-Type 2 (ANNA-2) Negative at <1:2
Antineuronal Nuclear Antibody-Type 3 (ANNA-3) Negative at <1:2
Anti-Glial/Neuronal Nuclear Antibody, Type 1 (AGNA-1) Negative at <1:2
Purkinje Cell Cytoplasmic Antibody, Type 1 (PCA-1) Negative at <1:2
Purkinje Cell Cytoplasmic Antibody, Type 2 (PCA-2) Negative at <1:2
Purkinje Cell Cytoplasmic Antibody, Type Tr (PCA-Tr) Negative at <1:2
Amphiphysin Antibody Negative at <1:2
CRMP-5-IgG Negative at <1:2

Note: Titers lower than 1:2 are detectable by recombinant CRMP-5 Western blot analysis. CRMP-5 Western blot analysis will be done on request on stored spinal fluid (held 4 weeks). This supplemental testing is recommended in cases of chorea, vision loss, cranial neuropathy, and myelopathy. Call the Neuroimmunology Laboratory at 800-533-1710 or 507-266-5700 to request CRMP-5 Western blot.
Synonyms Antineuronal Nuclear Antibody-Type 1; ANNA-1; Antineuronal Nuclear Antibody-Type 2; ANNA-2; Antineuronal Nuclear Antibody-Type 3; ANNA-3; Anti-Glial/neuronal Nuclear Antibody-Type 1; AGNA-1; Purkinje Cell Cytoplasmic Antibody-Type 1; PCA-1; Purkinje Cell Cytoplasmic Antibody-Type 2; PCA-2; Purkinje Cell Cytoplasmic Antibody-Type Tr; PCA-Tr; Amphiphysin Antibody; CRMP-5-IgG
Stability Room temperature 3 days, frozen 2 weeks.
Turn around times 1-2 weeks
Reflex? Additional testing may be initiated based on results of initial immunofluorescent screening assays aand separately charged.
CPT coding 86256-90 x 9, 84182-90 x 3, 86255-90, 86341-90
Last Updated 6/21/2016 07:49
Entry Number 1422
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