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Chlamydia trachomatis DNA detection from Throat & Rectal Samples (New test)

Item Value
Approval req'd? No
Available Stat? No
Test code P360
Test group Chlamydia
Performed by Quest
Sendout? Yes
Method Transcription-Mediated Amplification
Collection Instructions RECTAL: Use the APTIMA Unisex Swab Specimen Collection kit (white label). Insert the small, blue shafted collection swab (NOT the larger white shafted cleansing swab) approximately 3-5 cm into the rectum. Rotate swab against the rectal wall at least 3 times. Withdraw the swab carefully. Swabs that are grossly contaminated with feces should be discarded and the collection repeated. Remove the cap from the swab specimen transport tube and immediately place the swab into the transport tube. Carefully break the swab shaft at the score line. Re-cap the swab specimen transport tube tightly, label and ship to the lab.

THROAT: Use the Aptima Unisex Swab Specimen Collection kit (white label). Using a tongue depressor, insert the small, blue shafted collection swab (NOT the larger white shafted cleansing swab) and vigorously rub the tonsils and the posterior pharynx. Carefully remove the swab without touching any area of the mouth. Remove the cap from the swab specimen transport tube and immediately place the swab into the transport tube. Carefully break the swab shaft at the score line. Re-cap the swab specimen transport tube tightly, label and ship to the lab.
Container type Aptima Combo 2 Transport Media is stocked in Anal Neoplasia, Adolescent Medicine, and 360 Positive Care Clinics. It is also available from the MtZ laboratory and in Microbiology processing (L553) at Parnassus. Other sites/clinics should contact Microbiology at 415-353-1268 to arrange for supplies.
Amount to Collect One swab. Note: Both C. trachomatis and N. gonorrhoea can be tested from one swab
Sample type Throat or Rectal swab
UCSF Rejection Criteria Transport tube with larger white shafted cleansing swab, transport tube with non-GenProbe swabs, swab submitted in non-GenProbe transport tube
Processing notes Select the appropriate single or group test code depending on the sample site and order received.

Rectal Samples:
C. trachomatis/N. gonorrhoeae RNA, Rectal 16506X
N. gonorrhoeae RNA, Rectal 16504X
C. trachomatis RNA, Rectal 16505X

Throat samples:
C. trachomatis/N. gonorrhoeae RNA, Throat 70051X
N. gonorrhoeae RNA, Throat 70049X
C. trachomatis RNA, Throat 70048X
Normal range Not detected
Synonyms STD; Sexually transmitted disease
Stability Room temperature 1 month
Turn around times Set up 3x per week. Turnaround time 3-5 days.
Additional information Chlamydia trachomatis may infect the anal/rectal canal and oral/pharyngeal cavity of sexually active individuals. Detection of this organism may be important for determining the risk for disease progression or transmission.
The performance characteristics of this assay have been determined by Quest Diagnostics Nichols Institute, San Juan Capistrano.

A Positive Chlamydia trachomatis or Neisseria gonorrhoeae Nucleic Acid Amplification Test (NAAT) result should be considered presumptive evidence of infection. The result should be evaluated along with physical examination and other diagnostic findings. However, in cases of an unexpected Positive result, testing a second specimen using an alternative NAAT method may be beneficial. Contact the Microbiology Laboratory if testing by an alternative NAAT method is clinically indicated.
CPT coding 87491-90
Last Updated 1/30/2013 11:15:56 AM
Entry Number 1370

If you have additional questions regarding this test, please call: 415-353-1667

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