Click here for more information about laboratory operations and procedures
Bordetella pertussis Antibody (IgG/IgA)
| Item | Value | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Approval req'd? | No | ||||||||
| Available Stat? | No | ||||||||
| Utilization Guidelines | Serologic testing for B. pertussis infection includes IgG and IgA antibodies, which are seen in remote and recent infection, respectively. IgM antibodies are less sensitive and are not offered at UCSF. For diagnosis of active infection, PCR is the preferred method. | ||||||||
| Test code | BPAB | ||||||||
| Performed by | Focus via Quest | ||||||||
| Sendout? | Yes | ||||||||
| Method | Multi-Analyte Immunodetection (MAID) | ||||||||
| Container type | Red top | ||||||||
| Amount to Collect | 2 mL blood | ||||||||
| Sample type | Serum | ||||||||
| Preferred volume | 1 mL serum | ||||||||
| Min. Volume | 0.5 mL serum | ||||||||
| Processing notes | Allow blood to clot at room temperature and separate serum from cells within 2 hours of collection. Transfer serum to sterile, plastic screw-capped, aliquot tubes and store refrigerated or frozen. | ||||||||
| Units | IU/mL | ||||||||
| Normal range |
|
||||||||
| Synonyms | Whooping Cough; Haemophilus pertussis | ||||||||
| Turn around times | Test performed 5 days a week. Turnaround time: 1-3 days. | ||||||||
| Additional information | Some adult patients may develop a subacute illness characterized by a prolonged period of coughing-for a month or more-following Bordetella infection. As these patients have often been treated with antibiotics and because organisms often cannot found by PCR or culture in late stages of illness, an elevated antibody titer may be the only way to confirm the suspected diagnosis of adult pertussis. A rise in titer between paired sera, one collected within 1 week of onset of illness and another 2-3 weeks later, is most suggestive of a recent infection, but a single convalescent serum specimen will be accepted. Under some circumstances, sera can be forwarded to CDC for further evaluation. Serologic testing for B. pertussis infection includes IgG and IgA antibodies, which are seen in remote and recent infection, respectively. IgM antibodies are less sensitive and are not offered at UCSF. For diagnosis of active infection, PCR is the preferred method. |
||||||||
| CPT coding | 86615-90 x4 | ||||||||
| Last Updated | 9/17/2012 2:32:15 PM | ||||||||
| Entry Number | 136 |
If you have additional questions regarding this test, please call: 415-353-1667