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CSF Fungal Culture for Coccidiodes
|Utilization Guidelines||For diagnosis of yeast and Cryptococcal meningitis, recommended tests are: CSF bacterial culture (yeast, including Cryptococcus neoformans grow well on routine bacterial culture) CSF and serum Cryptococcal Antigen (CrAg)
Sensitivity of CSF Culture for Coccidiodes immitis is limited. Serum and / or CSF serology for Coccidioides (Coccidioides immitis Antibody, Immunodiffusion) are more sensitive than culture and are the recommended first-line diagnostic tests.
The yield of CSF cultures for other dimorphic fungi and invasive molds, including Aspergillus, Blastomyces, Histoplasma and the Zygomycetes (Mucor and Rhizopus) is extremely low. Tissue biopsy, if possible, is the recommended specimen for fungal diagnosis by culture.
|In House Availability||Set up daily, day and evening shifts|
|Container type||CSF tube or sterile collection tube|
|Amount to Collect||5-10 mL CSF|
|Preferred volume||5-10 mL CSF|
|Min. Volume||5 mL CSF|
|Normal range||No Coccidiodes isolated|
|Critical value||Positive culture|
|Synonyms||C. immitis; San Joaquin valley Fever|
|Stability||Refrigerated 24 hours|
|Turn around times||Up to 30 days|
|Additional information||Differentiation of Candida dublinensis from the biochemically and clinically similar species Candida albicans is performed on request only.
|Last Updated||12/19/2013 9:38:28 AM|