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Histoplasma capsulatum Antibody, by Complement Fixation

Item Value
Clinical Questions Does my patient have histoplasmosis?
Approval req'd? No
Available Stat? No
Test code HICFB
Test group Histoplasma
Performed by Focus via Quest
Sendout? Yes
Method Complemnent fixation
Collection Instructions Collect samples prior to performing fungal skin testing which can significantly increase antibody titers in sensitized individuals making results of this test uninterpretable.
Container type Gold top or Red top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.5 mL serum
UCSF Rejection Criteria Hemolysis, lipemia
Processing notes Order Quest test # 938X. For B&T patients order LabCorp test # 164319
Ref Lab Rejection Criteria Hemolysis, lipemia
Units Titer
Normal range < 1:8
Stability Room temperature 1 week, refrigerated 2 weeks, frozen at -20C 1 month.
Turn around times Test set up Monday - Friday, Turn around time 3-5 days
Additional information Patients should be screened by immunodiffusion before requesting complement fixation.

Titers to both mycelial and yeast phase antigens are reported, yeast phase antigen being more sensitive but less specific than mycelial phase antigen.

Cross reactions frequently occur with Blastomyces and Coccidioides.
CPT coding 86698-90 x2
LOINC code 20573-2
Last Updated 10/2/2010 11:53:08 AM
Entry Number 1258
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