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Array CGH, constitutional
|Test Update Information||Microarray results are reported based on the human genome build 19 (hg19/GRCh37). Cases prior December 1st, 2011, were reported based on hg18/NCBI36. Which human genome build is used must be noted when looking up regions in publically available databases.|
|Approval req'd?||Yes, if not ordered by Genetics, Neurology or Neonatal Intensive Care Unit faculty or fellows. Requests on inpatients require approval from Cytogenetics/Array staff.|
|Utilization Guidelines||Tests with long turn-around times (ie. Molecular based tests and Microarrays) should only be requested on an inpatient if the result is going to affect the inpatient management.
If the patient will likely be discharged before the result will be available, the test should be requested after discharge. (NOTE: UCSF Medical Center is not reimbursed for inpatient testing).
An exception to the above may be appropriate if there is a possibility the patient will not survive to be discharged and the information is important for diagnosis and/or family decisions/management (ie. recurrence risk).
|Performed by||Molecular Diagnostics (Microarray)|
|In House Availability||Set up once per week|
|Method||180K oligonucleotide CGH microarray using ISCA design
Click here to view probe locations
|Collection Instructions||Do not collect sample in heparin. Keep sample refrigerated for overnight or longer storage.
For UCSF Samples (from remote sites) Click here for sample collection instructions
For NON-UCSF Samples Click here for Requisition form & Account set-up instructions. Note we only do institutional billing.
|Container type||Lavender top preferred, Dark Green top acceptable|
|Amount to Collect||
|Sample type||EDTA or Herparinized whole blood, Extracted DNA, bone marrow|
|UCSF Rejection Criteria||Insufficient volume, unlabeled tubes, clotted samples, Samples received in Lithium-heparin (Lt. Green top) tubes|
|Processing notes||Refrigerate samples DO NOT CENTRIFUGE OR FREEZE.|
|Synonyms||Constitutional microarray; Oligo HDscan; aCGH; constitutional array CGH; chromosome microarray analysis; CMA; Oligoarray|
|Stability||Room temperature 4 days, refrigerated 2 weeks.|
|Turn around times||10-14 days|
|Additional information||For questions, contact the microarray laboratory at 514-8964|
|LDT or Mod FDA?||Yes|
|Last Updated||3/19/2013 9:23:32 AM|
If you have additional questions regarding this test, please call: 415-353-1667