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Lab Manual for Moffitt-Long and Mount Zion

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Albumin (Microalbumin), 24 hour urine

Item Value
Approval req'd? No
Available Stat? No
Test code AU24
Performed by Immunology
In House Availability Tuesday, Thursday, Saturday (day shift)
Method Nephelometry
Collection Instructions Refrigerate container during 24 hour collection
Container type 24 hour urine collection container

Click here for Urine Preservative Requirements
Amount to Collect Entire 24 hour urine output
Sample type 24 hour urine
Preferred volume 2 mL urine
Min. Volume 0.5 mL urine
UCSF Rejection Criteria Container not refrigerated during collection.
Processing notes Aliquot 2 mL. Note volume and hours collected. Order AU24.
Units mg/D
Normal range 24 hour collection:
Normal < 30 mg/D
Microalbuminuria 30-299 mg/D
Nephropathy > 300 mg/D
Synonyms Microalbuminuria
Turn around times 1-3 days
Additional information Diabetes mellitus is one of the commonest causes of end-stage renal disease. The National Kidney Foundation recommends that diabetics > 12 years old be tested yearly for microalbuminuria if the rate of excretion is within normal limits (Amer J Kid Dis. 1995;25:107). The Diabetes Coalition of California recommends annual testing for microalbuminuria beginning 5 years after the diagnosis of type I diabetes mellitus and beginning at diagnosis of type II disease. The cost benefit of these strategies are not established.

Transient increases in urinary albumin excretion are seen with heavy exercise, urinary infection, acute febrile illness, heart failure and following the administration of NSIADs or ACE inhibitors, all of which should be avoided during screening. Because of the difficulty in collecting and accurately timing 24 hour samples, a spot collection is recommended and the albumin excretion is normalized for creatinine excretion, correcting to some extent for the diurnal fluctuation in urinary output. Abnormalities should be verified by a repeatedly positive assay within 6-12 weeks before a diagnosis of diabetic microalbuminuria or diabetic nephropathy is made.
CPT coding 82043
Last Updated 3/24/2013 7:13:39 PM
Entry Number 1146
Lab Procedure Link Click here for Procedure

If you have additional questions regarding this test, please call: 415-353-1667

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