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Porphobilinogen, Quantitative, random urine

Item Value
Clinical Questions Does my patient have acute porphyria?
Approval req'd? No
Available Stat? No
Test code PBQTRU
Test group Porphobilinogen
Performed by Quest
Sendout? Yes
Method Colorimetric
Collection Instructions Collect random urine, wrap collection cup in aluminum foil to protect sample from light. Transport asap to laboratory for processing. If transport delayed the sample should be refrigerated.
Container type Urine cup, wrap with foil to protect from light.
Amount to Collect 10 mL
Sample type Random urine
Preferred volume 10 mL urine
Min. Volume 2 mL urine
UCSF Rejection Criteria Sample was not protected from light.
Processing notes Do not use preservatives. Aliquot to dark pour off tube or wrap with aluminum foil to protect from light. Freeze at -20C and ship frozen on dry ice.
Units mg/g creatinine
Normal range
1-8 years 0.9-2.8 mg/g creatinine
9-17 years 0.5-2.0 mg/g creatinine
≥ 18 years ≤ 1.5 mg/g creatinine
Synonyms PBG; Porphyrin precursors; Porphyria
Stability Room temperature not acceptable, refrigerated 1 week, frozen at -20C 1 month.
Turn around times Set up 5x per week. Turnaround 3-5 days
Additional information
Disorder Porphobilinogen Increased?**
Acute intermittent porphyria +
ALA dehydratase deficiency porphyria +
Congenital erythropoietic coproporphyia -
Erythropoietic protoporphyria -
Hepatoerythropoietic porphyria -
Hereditary coproporphyria +/-
Porphyria cutanea tarda -
Variegate porphyria +/-

** Patients with hereditary forms of porphyria usually will present with profound elevations of this analyte (> 5-fold) during acute episodes. Moderate elevations (< 3-fold) are more often due to medications or environmental factors.
CPT coding 84110-90
LOINC code 13797-6
Last Updated 2/3/2016 2:24:48 PM
Entry Number 1119
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