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Topiramate
| Item | Value | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Approval req'd? | No | ||||||||||||
| Available Stat? | No | ||||||||||||
| Test code | TOPA | ||||||||||||
| Performed by | Quest | ||||||||||||
| Sendout? | Yes | ||||||||||||
| Method | Flourescent polarization immunoassay | ||||||||||||
| Collection Instructions | Draw peak 2-4 hours after dose, trough 0.5-1 hour before dose when patient is at steady state. Avoid hemolysis | ||||||||||||
| Container type | Red top preferred, Dark green top acceptable (Gold top unacceptable) | ||||||||||||
| Amount to Collect | 2 mL blood | ||||||||||||
| Sample type | Serum (plasma acceptable) | ||||||||||||
| Preferred volume | 1 mL serum or plasma | ||||||||||||
| Min. Volume | 0.5 mL serum or plasma | ||||||||||||
| UCSF Rejection Criteria | Drawn in Gold top or Light green top vacutainer. Hemolysis, Lipemia | ||||||||||||
| Processing notes | Maintain sample at room temperature. Order Quest # 30965 | ||||||||||||
| Units | µg/mL (mcg/mL) | ||||||||||||
| Normal range |
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| Synonyms | Topamax | ||||||||||||
| Stability | Room temperature 1 week, refrigerated 2 weeks, frozen at -20C 1 month | ||||||||||||
| Turn around times | Performed 5x per week. Turnaround 4-8 days | ||||||||||||
| Additional information | Topiramate is an antidepressant used as an adjunctive treatment of partial epilepsy and Lennox-Gastaut syndrome in children. Monitoring is useful to optimize dose and avoid toxicity. | ||||||||||||
| CPT coding | 80201-90 | ||||||||||||
| LOINC code | 17713-9 | ||||||||||||
| Last Updated | 7/31/2012 9:35:07 AM | ||||||||||||
| Entry Number | 1108 |
If you have additional questions regarding this test, please call: 415-353-1667