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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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Monitoring Anticoagulation

Item Value
Approval req'd? No
Available Stat? No
Test code
Container type
Sample type
Normal range
Additional information Recommendations regarding anticoagulation and monitoring of anticoagulation can be obtained from the Adult Hematology Consultation service, which can be contacted at pager 443-4276. For Pediatric Hematology Consultation service, contact pager 443-6966.

For reference purposes, this laboratory manual contains information regarding monitoring of anticoagulation as noted below.

Monitoring of Unfractionated Heparin Therapy:
Usual method: Click here for PTT
Special circumstances: Click here for Heparin Level
Click here for Heparin Laboratory/Dosing Algorithm

Monitoring of Low Molecular Weight Heparin:
Click here for Heparin Level (LMWH)

Monitoring of Fondaparinux:
Click here for Fondaparinux

Monitoring of Direct Thrombin Inhibitors (i.e. Argatroban, Bivalirudin):
Click here for PTT

For Argatroban a specific assay is available: Click here for Argatroban

No specific assay is available on site for measurement of Bivalirudin. Recommendations for bivalirudin therapy and monitoring are available through the Hematology Consultation services: for adults pager 443-4276 and for pediatrics pager 443-6966. [Bivalirudin may be monitored by aPTT or by ACT (only available for patients monitored at point of care). For additional information on detection or measurement of bivalirudin, please contact the hematology laboratory at 415-353-1747 and ask for the laboratory medicine resident (regular working hours) or ask to be connected to the laboratory medicine resident on-call.

Monitoring of Warfarin:
Click here for Prothrombin Time/INR

Monitoring of Target Specific Oral Anticoagulants (TSOACs) including dabigatran, apixaban, edoxaban, and rivaroxaban:
These medications are generally used without monitoring.
For Rivaroxaban a specific assay is available:

Click here for Rivarobaxan

See also information available at the UCSF CareLinks Website, which includes guidelines, protocols, and order forms for anticoagulation:
Click here
Last Updated 6/23/2015 12:04:05 PM
Entry Number 1096
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