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Delta-Aminolevulinic Acid Quantitative, random urine

Item Value
Clinical Questions Does my patient have acute porphyria?
Available Stat? No
Test code ALAQR
Test group D-ALA
Performed by Quest
Sendout? Yes
Method Colorimetric
Patient Preparation Do not use first morning void, late evening specimen (after 8:00 pm), or specimen after excessive fluid intake. Recommend patient to collect urine specimen and submit to laboratory on-site to maintain specimen stability.
Collection Instructions Cover urine cup with foil to protect sample from light and refrigerate.
Container type Urine cup wrapped in aluminum foil.
Amount to Collect See preferred volume
Sample type Random urine
Preferred volume 2 mL urine
Min. Volume 0.6 mL urine
Processing notes Aliquot urine into a dark brown tube and refrigerate. Order Quest test # 6301.
Units mg/g creatinine
Normal range Pediatric:
1 - 8 years 2.3-6.2 mg/g creat
9 - 17 years 1.5-5.3 mg/g creat

≥ 18 years:
Females <5.4 mg/g creat
Males <1.8 mg/g creat

Synonyms ALA; D-ALA; DALA; D-aminolevulenic acid; Porphyrin precursors; Porphyria
Stability Room temperature unaccceptable, refrigerated 1 week, frozen at -20C 1 month.
Turn around times Test run 2x per week. TAT 6-8 days
Additional information This test is the usual first step in the diagnosis acute intermittent porphyria. Patients with hereditary forms of porphyria usually will present with profound elevations of this analyte (> 5-fold) during acute episodes. Moderate elevations (< 3-fold) are more often due to medications or enviromental factors.
CPT coding 82135-90
LOINC code 13728-1
Last Updated 6/14/2016 3:22:30 PM
Entry Number 1086
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