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Pneumococcal IgG Antibodies (6 serotypes)
| Item | Value |
|---|---|
| Approval req'd? | No |
| Available Stat? | No |
| Test code | APN6 |
| Test group | Pneumococcal |
| Performed by | Quest |
| Sendout? | Yes |
| Method | Multiple Analyte Immuno Detection (MAID) |
| Collection Instructions | Pneumococcal vaccine response testing should be performed with paired pre- and post-vaccination sera. Please indicate on request form if the specimen is pre- or post-vaccination collections. Label samples "PRE" or "POST". |
| Container type | Gold top, Red top |
| Amount to Collect | 2 mL blood |
| Sample type | Serum |
| Preferred volume | 1 mL serum |
| Min. Volume | 0.5 ml serum |
| Processing notes | Freeze aliquot at -20C. Order Quest test #34263X |
| Units | µg/mL (mcg/mL) |
| Normal range | See additional information |
| Synonyms | Pneumococcal serology |
| Stability | Room temperature 7 days, refrigerated 14 days, frozen at -20C 1 month. |
| Additional information | Serotypes tested for include: 1, 3, 14, 19 (19F), 23 (23F), 51 (7F) Note: Serotype designations are American nomenclature, with Danish nomenclature in parenthesis. The protective concentration of S.pneumoniae antibodies remains undefined. Evaluation of the pneumococcal vaccine response is best accomplished by comparing pre-vaccination and post-vaccination antibody levels. A 2-4 fold increase in type-specific antibodies measured after 4-6 weeks after vaccination is expected in immunocompetent adults. The number of serotypes for which a 2-to-4 fold increase is observed varies greatly among individuals, and no distinct response pattern has been linked to protection. Adults > 65 years old may exhibit a smaller (< 2-fold) increase in type-specific antibody levels. |
| CPT coding | 86317-90 x6 |
| LOINC code | 42771-6 |
| Last Updated | 9/30/2011 12:21:56 PM |
| Entry Number | 1081 |
If you have additional questions regarding this test, please call: 415-353-1667