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Pneumococcal IgG Antibodies (14 serotypes)
|Method||Multiple Analyte Immuno Detection (MAID)|
|Collection Instructions||Pneumococcal vaccine response testing should be performed with paired pre- and post-vaccination sera. Please indicate on request form if the specimen is pre- or post-vaccination collections. Label samples "PRE" or "POST".|
|Container type||Gold top, Red top|
|Amount to Collect||2 mL blood|
|Preferred volume||1 mL serum|
|Min. Volume||0.5 mL serum|
|Processing notes||Freeze aliquot at -20C. Order Quest test # 19564X|
|Normal range||See additional Information|
|Stability||Room temperature 7 days, refrigerated 14 days, frozen at -20C 1 month.|
|Additional information||Serotypes tested for include: 1, 3, 4, 5, 8, 9 (9N), 12 (12F), 14, 19 (19F), 23 (23F), 26 (6B), 51 (7F), 56 (18C), 68 (9V)
Note: Serotype designations are American nomenclature, with Danish nomenclature in parenthesis.
The MAID procedure measures IgG antibodies recognizing 14 type-specific pneumococcal polysaccharide antigens included in the polyvalent vaccine.
Evaluation of response to vaccinatioon is best accomplished by com paring Pre-vaccination levels and levels obtained 4-6 weeks post vaccination. A 2-fold to 4-fold increase in 70% of the pneumococcal serotypes vaccinated for in immunocompetent patients between the ages of 5 and 65 years. Adults over the age of 65 may respond with less than 2-fold increases in antibody levels.
|CPT coding||86317-90 x14|
|Last Updated||9/30/2011 12:21:35 PM|