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If you have additional questions regarding this test, please call: 415-353-1667
QuantiFERON Gold TB
|Approval req'd?||Yes, inpatients, except liver and kidney transplant service, require approval by ID service|
|Collection Instructions|| Note it is mandatory the the tubes be filled correctly as underfilled or overfilled tubes will be rejected by Quest.
COLLECT SAMPLE 4 AM - 2 PM ON MONDAY-THURSDAY ONLY. DO NOT COLLECT SAMPLE ON UCSF OBSERVED HOLIDAYS OR THE DAY BEFORE HOLIDAYS. .
COLLECT BETWEEN 7 AM – 2 PM ON MONDAY – THURSDAY BY UCSF LABORATORY STAFF AT OUR OUTPATIENT FACILITIES. DO NOT COLLECT SAMPLE ON UCSF OBSERVED HOLIDAYS OR THE DAY BEFORE HOLIDAYS.
1. For Parnassus and Mission Bay inpatient only, pick up collection
kits from Laboratory Central Processing. Outpatient clinics will have
their own collection kits.
2. Collect 1 ml of blood by venipuncture directly into each of the three
tubes (Nil, TB Antigen, Mitogen). Fill each tube up to the black
mark. Under or overfilling of the tubes may lead to erroneous
3. Mix the tubes by shaking firmly and vertically for 10 times and label tubes appropriately.
4. These are time sensitive samples, please deliver the tubes to the
Laboratory Central Processing immediately.
|Container type|| Requires special collection kit available from central laboratory containing:
Note it is mandatory the the tubes be filled correctly as underfilled or overfilled tubes will be rejected by Quest.
|Amount to Collect||3 mL blood, place 1 mL of blood into each tube in the collection kit|
|Sample type||Whole blood|
|Preferred volume||3 mL blood, place 1 mL of blood into each tube in the collection kit|
|Min. Volume||3 mL blood, place 1 mL of blood into each tube in the collection kit|
|UCSF Rejection Criteria||Frozen samples. Improperly collected samples.|
|Processing notes||CENTRAL PROCESSING STAFF:
Accession the samples immediately upon receipt and send to Immunology at China Basin in room temperature. Samples received after 2 PM please verify with China Basin processor before rejecting
|Ref Lab Rejection Criteria||Overfilled or underfilled tubes received.|
|Normal range||Not detected|
|Synonyms||Tuberculosis; TB; TB skin test; Interferon gamma; IFN gamma|
|Stability||Samples need to be incubated at China Basin as soon as possible after collection (within 16 hours of collection).|
|Turn around times||5-7 days|
|Additional information||The QuantiFERON test detects the release of IFN-gamma released by whole blood lymphocytes after incubation with tuberculin purified protein derivative and phytohemagglutinin.
The test is intended for screening asymptomatic individuals who may be at risk for latent tuberculosis (recent immigrants, prisoners and prison/jail employees) or TB exposure (military, hospital personnel). In these settings it is equivalent but no better than skin testing.
QuanitFERON testing may be more specific than skin testing when screening individuals with a history of prior BCG vaccination.
It is NOT recommended for use in patients with symptoms of active TB (known to cause decreased IFN-G responses), contacts of patients with active TB, immunosuppressed patients, patients with diabetes, silicosis, chronic renal failure, leukemia, lymphoma, head/neck cancer, lung cancer, s/p gastrectomy or jejunoileal bypass. In these situations skin testing is recommended.
|Last Updated||11/18/2016 4:16:04 PM|