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Lab Manual for Moffitt-Long and Mount Zion

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Leflunomide

Item Value
Approval req'd? No
Available Stat? No
Test code LEFL
Performed by Quest
Sendout? Yes
Method LC/MS
Container type Red top (Gold top NOT acceptable)
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
UCSF Rejection Criteria Collected in Gold top
Processing notes Refrigerate sample. Order Quest test #18865
Units ng/mL
Normal range See Additional Information
Synonyms Teriflunomide
Turn around times 7 days
Additional information This test reports the active metabolite of Teriflunomide. Women who are being treated with Leflunomide and desire to become pregnant it is recommended that the plasma Teriflunomide levels be less than 20 ng/mL by two separate tests taken at least 14 days apart. Mean steady state trough plasma concentrations of Teriflunomide from patients on daily regimen of 5,10 or 25 mg of Leflunomide were 8,800 , 18,000 and 63,000 ng/mL respectively. The minimum effective concentration is reported to be 13,000 ng/mL.

This test was developed, validated and performed by National Medical Services Inc. 3701 Welsh Road, Willow Grove, PA. 19090 via Quest Nichols Diagnostics.
CPT coding 82542-90
LOINC code 38901-5
Last Updated 10/28/2013 11:49:04 AM
Entry Number 1053

If you have additional questions regarding this test, please call: 415-353-1667

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