UCSF Pathology & Lab Medicine Physician-Scientist Pathway
For More Information
- Scott André Oakes, MD
- Phone: (415) 476-1777
- Fax: (415) 514-3165
- UCSF Department of Pathology
- 513 Parnassus Avenue
- Room HSW-517, Box 0511
- San Francisco, CA 94143-0511
The UCSF Departments of Pathology and Laboratory Medicine are deeply committed to training the next generation of basic scientists who will work at the interface of science and medicine. To achieve this, our joint residency program each year invites several highly accomplished entering residents who are committed to a career in basic biomedical research to enroll in the Physician-Scientist Pathway (PSP). The goal of this program is to provide advanced training in the experimental study of the molecular and cellular basis of disease that will permit the trainee to establish him or herself as independently funded investigator in a career blending basic science with clinical medicine. This is achieved through providing a structured series of seminars, lectures, and journal clubs during the clinical years, followed by two or more years of post-residency research training in any laboratory at UCSF, one of the leading biomedical research institutions in the world. The Departments of Pathology and Laboratory Medicine have a strong track record of guiding physician-scientists through the process of career development, by providing mentors and role models from among the research faculty, and these resources will be available to program participants.
The PSP offers the following benefits:
- Admission to the UCSF clinical subspecialty fellowship of the applicant’s choice (contingent upon satisfactory completion of the core residency program, application at least 18 months prior to the fellowship starting date and approval of the fellowship director).
- Guaranteed support for post-doctoral research training. Participants in the PSP are guaranteed funding for up to two years of post-residency research in any laboratory at UCSF in the event that funds are not received from granting agencies.
- Counseling from senior faculty on topics including selecting a laboratory, writing grant applications, and making the most of your residency and post-doctoral training, through a series of formal seminars and informal discussions.
- A personal faculty advisor who will provide guidance on establishing a career as an independent investigator.
- Participation in a monthly Research Interest Group meeting, where faculty and fellows present and discuss their work.
The American Board of Pathology (ABP) has recently announced a "Physician-Scientist Research Pathway" for Pathology. This pathway requires a minimum of 12 months of research in addition to the 6 months of research that is already included in the core residency, and does not guarantee financial support. At UCSF, we do not require physician-scientist trainees to join this pathway, but prefer to work with our fellows to craft individual training programs to best achieve their goal of becoming a principal investigator . It is also important to emphasize that we guarantee at least two years of financial support for research training (in most cases trainees spend significantly more than two years doing research after finishing their clinical training). We also recommend that trainees entering the UCSF PSP should do their clinical training in AP, CP or AP-NP, in order to maintain a clear focus on their scientific goals and to limit the duration of training to the extent possible.
UCSF has two world-class graduate (PhD) programs in the life sciences, the Program in Biological Sciences (PIBS) and Biomedical Sciences (BMS), each of which offers advanced coursework in basic and applied biology. A full listing of the available courses can be found at their websites (PIBS can be found at http://pibs.ucsf.edu/and BMS can be found at http://bms.ucsf.edu/). PSP fellows who wish to do so may audit any of these courses as a way to deepen their exposure to areas of interest.
- Abul K. Abbas, MBBS
- T cell biology, autoimmunity
- Boris Bastian, MD
- Genetics and biology of melanoma
- Robert Blelloch, MD, PhD
- Molecular basis of stem cell self-renewal, differentiation and contribution to cancer
- Michael P. Busch, MD, PhD
- Blood safety and transfusion medicine
- Stephen J. DeArmond, MD, PhD
- Prion diseases
- Jayanta Debnath, MD
- Autophagy and cancer pathogenesis
- Walter E. Finkbeiner, MD, PhD
- Cystic fibrosis and lung inflammation
- Eric J. Huang, MD, PhD
- Neural development and neurodegenerative disease
- Scott C. Kogan, MD
- Leukemia pathogenesis
- Matthew Krummel, PhD
- Immune cell interactions, imaging
- Marta Margeta, MD, PhD
- Pathogenesis of nerve and muscle diseases
- Andrew D. Leavitt, MD
- Hematopoietic stem cells
- Clifford A. Lowell, MD, PhD
- Innate immune cell signal transduction
- Markus Müschen, MD, PhD
- Blood cell development and leukemogenesis
- Stephen Nishimura, MD
- Integrins and lung inflammation
- Scott André Oakes, MD
- Apoptosis in response to cell injury
- Joanna J. Phillips, MD, PhD
- Glioblastoma and tumor microenvironment
- Mark Seielstad, PhD
- Genetic epidemiology
- Bradley A. Stohr, MD, PhD
- Telomeres and DNA damage responses
- Thea Tlsty, PhD
- Cancer progression, genomic instability
- Laura J. Van't Veer, PhD
- Cancer genetics, breast cancer biomarkers
- Alan H.B. Wu, PhD
- Pharmacogenomics and toxicology
How to Apply
Interested applicants should inform Dr. Scott Oakes by e-mail (Scott.Oakes@ucsf.edu) of their interest in the program at the time they submit their ERAS application for residency. Please note that the application deadline for the PSP is December 1st, 2014, which is 2 weeks prior to the deadline of December 15th for applications to the residency training program. Applicants chosen to interview will be required to attend a special PSP interview and information day on either Thursday, December 11, 2014 or Thursday, January 8, 2015, which will feature presentations by and conversations with PSP faculty. Regular interviews for residency programs will be arranged for the either the preceding or following days, and should leave time for applicants to explore more of UCSF and San Francisco on their own according to their interests.