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Tarik Tihan, MD, PhD

Research and Clinical Interests

My goal is to develop a better understanding of the critical elements for histological classification of primary CNS neoplasms with specific emphasis on pediatric brain tumors, their distinctive subtypes and prognostic markers for each subtype. Our observations contributed to the understanding of biological behavior and molecular features in some tumors such as pilomyxoid astrocytomas. My laboratory actively collaborates with many colleagues from the Brain Tumor Research Center, UCSF, and scientists from other institutions such as Johns Hopkins University, Stanford University, and the Mayo Clinic to better define entities, and novel prognostic markers. I participate in the activities of California Childhood Brain Tumor Consortium, Children’s Oncology Group and WHO Classification of Tumours of the Nervous System. I take an active role in our professional organizations as the Vice President for Professional Affairs of the American Association for Neuropathologists. I also function as a member of the test material development committee of the NBME for Step I examination.

Selected Publications

  • Phillips JJ, Misra A, Feuerstein BG, Kunwar S, Tihan T. Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization. Arch Pathol Lab Med 2010;134:1063-1069.
  • Sughrue ME, Kaur R, Kane AJ, et al. Intratumoral hemorrhage and fibrosis in vestibular schwannoma: a possible mechanism for hearing loss. J Neurosurg 2010. (Epub ahead of publication)
  • Swartling FJ, Grimmer MR, Hackett CS, et al. Pleiotropic role for MYCN in medulloblastoma. Genes Dev 2010;24:1059-1072.
  • Tihan T, Bloomer MM. Astrocytic neoplasms of the central nervous system and orbit: a morphologic perspective. Seminars in Diagnostic Pathology 2010;27:114-121.
  • Waldron JS, Yang I, Han S, et al. Implications for immunotherapy of tumor-mediated T-cell apoptosis associated with loss of the tumor suppressor PTEN in glioblastoma. J Clin Neurosci 2010. (Epub ahead of publication)
  • Yang I, Tihan T, Han SJ, et al. CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival. J Clin Neurosci 2010 (Epub ahead of publication).

Selected Awards

  • 2001-2002 W Barry Wood Jr. Award for Teaching Excellence, JHU Medical School
  • 2002-2003 UCSF Department of Pathology Teaching Excellence Award
  • 2002-2003 UCSF Department of Neurological Surgery, Diane RalstonTeaching Award
  • 2004-2005 UCSF Department of Neurological Surgery Diane Ralston Teaching Award
  • 2008 Ege Pathology Society Recognition of Scientific Contribution
  • 2008 Cukurova Pathology Society Award for Contribution to Pathology Education
  • 2009 AWADIAP, Friends of Africa Certificate of Recognition
  • 2010 Moroccon Hematology and Pediatric Oncology Society Certificate of Recognition
  • 2010 Ankara Pathology Society Certificate of Recognition

Additional Information

Tarik Tihan, MD, PhD
  • Professor of Pathology
  • Pathology
  • Neuropathology

Specialty Area

Neuropathology

Contact Information

  • Neuropathology Unit
  • 505 Parnassus Avenue, Room M551
  • San Francisco, CA 94143-0102

Other UCSF Organizational Association(s)

  • Brain Tumor Research Center

Hospital Affiliation(s)

  • UCSF Medical Center
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