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Chuanyi Mark Lu, MD

Research and Clinical Interests

Major areas of interest include laboratory hematology and coagulation, hematopathology, laboratory management, and medical education. Primary research focus is translational research in laboratory assay development and in hematological and cardiovascular disorders.

Selected Publications

  • Lu C, Giordano FJ, Bao X, Morris KC, Rothman A. Antisense fosB RNA inhibits thrombin-induced hypertrophy in cultured pulmonary arterial smooth muscle cells. Circulation 1998; 98:596-603.
  • Bao X, Lu C, Frangos JA. Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: Role of NO, NFkB, and egr-1. Arterioscler Thromb Vasc Biol 1999; 19:996-1003.
  • Lu CM, et al. Mass spectrometric immunoassay for parathyroid hormone-related protein. Anal Chem 2002; 74:5507-12.
  • Lu CM, et al. Concurrent acute myeloid leukemia with inv(16)(p13.1q22) and chronic lymphocytic leukemia: molecular evidence of two separate diseases. Am J Hematol 2006; 81:963-968.
  • Lu CM, et al. Simultaneous presence of major chromosomal abnormalities in blasts crisis of chronic myeloid leukemia. Cancer Genet Cytogenet 2007; 172:174-175.
  • Bao X, Lu CM, et al. Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse. Circulation. 2007;116(9):1024-31.
  • Bao X, Lu CM, et al. Impaired chronotropic response to exercise in mice lacking catecholamines in adrenergic cells. Ann N Y Acad Sci. 2008;1148:297-301.


  • Lu CM. Section VI: Immunophenotyping markers. In Tietz Clinical Guide to Laboratory Tests, fourth edition, Saunders Elsevier 2006.
  • Nicoll D, McPhee S, Pignone M, Lu CM. Pocket Guide to Diagnostic Tests, fifth edition, McGraw Hill 2008.
  • Lu CM. Flow Cytometry Testing. In: Self-Assessment in Clinical Laboratory Science II. AACC Press, 2008.
  • Nicoll D, Lu CM. Diagnostic Testing & Medical Decision Making (Online Chapter 43); Therapeutic Drug Monitoring & Laboratory Reference Intervals (Appendix). In: 2010 Current Medical Diagnosis & Treatment (CMDT), McGraw Hill, 2009.

Selected Awards

  • Teaching Scholar, Teaching Scholars Program (TSP), University of California San Francisco School of Medicine, 2005-2006.
  • Faculty Teaching Award, Department of Laboratory Medicine, University of California San Francisco, 2003-2004.
  • Paul E. Strandjord Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists, 2001.

Additional Information

C. Mark Lu, MD, PhD
  • Professor and Vice Chair, UCSF Depart of Laboratory Medicine; Chief, Laboratory Medicine Service & Director, Hematology & Hematopathology, San Francisco VA Healthcare System
  • Laboratory Medicine
  • Hematology

Specialty Area

Hematology, Coagulation, Hematopathology

Contact Information

Mailing/Shipping Address:

  • Lab Medicine Service (113A)
  • Veterans Affairs Medical Center
  • 4150 Clement St
  • San Francisco, CA 94121

Hospital Affiliation(s)

  • Veterans Affairs Medical Center
  • UCSF Medical Center
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