Laurence J. Marton, MD
Research and Clinical Interests
Polyamines, epigenetics, drug development
Selected Publications
- Casero RA Jr, Marton LJ. Polyamine Metabolism and Function: A Target Rich Environment in the Battle Against Cancer and Other Hyperproliferative Diseases. Nature Reviews: Drug Discovery 6:373-390, 2007
- Huang Y, Murray Stewart T, Wu Y, Baylin SB, Marton LJ, Perkins B, Jones RJ, Woster PM, Casero Jr RA. Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 (LSD1) and Induce Re-Expression of Epigenetically Silenced Genes. Clin Cancer Res 15:7217-7228, 2009
- Kuo W-L, Das D, Ziyad S, Bhattacharya S, Gibb WJ, Heiser LM, Sadanandam A, Fontenay GV, Hu Z, Wang NJ, Bayani N, Feiler HS, Neve RM, Wyrobek AJ, Spellman PT, Marton LJ, Gray JW. A Systems Analysis of the Chemosensitivity of Breast Cancer Cells to the Polyamine Analog PG-11047. BMC Medicine: http://www.biomedcentral.com/1741-7015/7/77 2009
Selected Awards
- Distinguished Alumnus Award, Albert Einstein College of Medicine
- Honorary Doctorate, Yeshiva University
- Adjunct Professor
- Laboratory Medicine
Contact Information
- ljmarton@
gmail.com - Phone: (650) 494-1818
- 581 Military Way
- Palo Alto, CA 94306