Jingwei Yu, PhD, MM

Research and Clinical Interests

Chromosome microdissection and DNA array-based genomic analysis of diseases, in particular, chromosome disorders and cancer.

Kao FT, Yu JW. Chromosome microdissection and cloning in human genome and genetic disease analysis. Proc Natl Acad Sci U S A. 88: 1844-8, 1991.
Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Peltomäki P, Sistonen P, Aaltonen LA, Nyström-Lahti M, Guan XY, Zhang J, Meltzer PS, Yu JW, Kao FT, Chen DJ, Gerosaletti KM, Fournier REK, Todd S, Lewis T, Leach RJ, Naylor SL, Weissenbach J, Mecklin JP, Jarvinen H, Petersen GM, Hamilton SR, Green J, Jass J, Watson P, Lynch HT, Trent JM, de la Chapelle A, Kinzler KW and Vogelstein B. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell. 75: 1215-25, 1993.
Yu J, Tong S, Shen Y, Kao FT. Gene identification and DNA sequence analysis in the GC-poor 20 megabase region of human chromosome 21. Proc Natl Acad Sci U S A. 94: 6862-7, 1997.
Qi Z, Hoffman G, Kurtycz D, Yu J. Prevalence of the C677T substitution of the methylenetetrahydrofolate reductase (MTHFR) gene in Wisconsin. Genet Med. 5: 458-9, 2003.
Rice GM, Qi Z, Selzer R, Richmond T, Thompson K, Pauli RM, Yu J. Microdissection-based high-resolution genomic array analysis of two patients with cytogenetically identical interstitial deletions of chromosome 1q but distinct clinical phenotypes. Am J Med Genet A. 140: 1637-43, 2006.