Gary A. Jarvis, PhD
Research and Clinical Interests
My research interests include: 1) Regulation of complement activation by blood-borne Gram-negative bacteria; 2) Development of vaccines for meningococcal meningitis and gonorrhea; 3) Complement deficiencies and susceptibility to bacterial sepsis; 4) Role of innate immune receptors in Gram-negative bacterial infections.
- Quan, D. N., M. D. Cooper, J. L. Potter, M. H. Roberts, H. Cheng, and G. A. Jarvis. 2008. TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells. Mucosal Immunol. 1:229-238.
- John, C. M., M. Liu, and G. A. Jarvis. 2009. Profiles of structural heterogeneity in native lipooligosaccharides of Neisseria and cytokine induction. J. Lipid Res. 50:424-438.
- John, C. M., M. Liu, and G. A. Jarvis. 2009. Natural phosphoryl and acyl variants of lipid A from Neisseria meningitidis strain 89I differentially induce TNF-α in human monocytes. J. Biol. Chem. 284:21515-21525.
- Ding, J., A. Rapista, N. Teleshova, G. Mosoyan, G. A. Jarvis, M. E. Klotman, and T. L. Chang. 2010. Neissseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation J. Immunol. 184:2814-2824.
- Laboratory Medicine
- Infectious Diseases
- Gram-negative bacterial infections
- Phone: (415) 221-4810, ext. 2303
- Fax: (415) 221-7542
- VA Medical Center,
- Dept. 111W1, 4150 Clement Street,
- San Francisco, CA 94121